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Glory Boughton, thirty-eight, returns to her family home in Gilead, Iowa to care for her dying father, the Reverend Robert Boughton. Her brother Jack — the family's prodigal son, gone for twenty years — comes home too, seeking refuge and trying to make peace with a past marked by trouble and disappointment. Set concurrently with Gilead and telling many of the same events from the Boughton family's side, the novel traces the difficult reconciliation between a father and the son he cannot stop loving.